Posting on social media, the restaurant said that its last service would be 16 April and that the time was right to close.
"It is with heavy hearts that we announce the closure of Mere restaurant - but we feel this is the right time after 7yrs," it wrote.
"We want to take this opportunity to wholeheartedly thank Alastair Storey and everyone who has supported us and our loyal patrons and dedicated staff throughout this journey.
"To our customers we thank you for your loyal and joyous visits. We hope to raise one last glass together before we close."
Mere opened in Fitzrovia in 2017 serving a menu based on Galetti’s classic French cooking background honed during her years as senior sous chef at Le Gavroche in Mayfair, while also drawing on her Samoan heritage and her time living in New Zealand, where she moved when she was eight years old.
In September last year Sven-Hanson Britt has joined the restaurant as head chef, two months after closing his own London restaurant Oxeye.
Galetti is one of a number of high-profile chefs to close their London restaurants in recent months. Fellow MasterChef The Professionals judge Marcus Wareing closed his restaurant at The Berkeley at the end of last year and Jason Atherton recently announced the closure of Pollen Street Social after 13 years.
The restaurant added: “Here’s to the next adventure.”