Neville’s two Manchester hotels - which he co-owns with fellow ex-professional football player Ryan Giggs - will be closed to the public, freeing 176 beds for NHS and other medical staff.
The defender and former Manchester United captain also said that none of his staff at either the Stock Exchange Hotel and Hotel Football will be made redundant or asked to take unpaid leave.
“It is something we are delighted to have been able to come to an agreement with,” Neville said.
“It is at this moment in time that the whole of our industry needs to show solidarity, not just for our staff in these uncertain times, but for the people who need the accommodation most in the coming months. It will be free of charge and out staff will continue to operate the hotels as normal,” Neville said in a video posted on Twitter that has been viewed in excess of 7m times.
“It’s obviously very difficult times and we hope we can go out of this stronger as a hotel business beyond what’s happening.”
The two hotels will close to the public this Sunday (22 March).
Hotels are facing huge losses as the Coronavirus crises intensifies. Other hotels to offer up beds to health care professionals include Chelsea's Stamford Bridge hotel.
Best Western Great Britain - the UK's largest independent hotel group - said it would consider turning some its hotels into makeshift hospitals.