The company, owned by entrepreneur Robert Earl, will open the new 150-cover restaurant at the Village Hotel in Elstree, London on 19 September.
Earl, who also has restaurants within Village Hotels at Blackpool, Newcastle, Swindon and the Wirral, said he was pleased that the concept was appealing to a growing number of customers.
"The Brits have always loved Italian cuisine and with our authentic, quality food served in generous portions we hope to continue our success across the UK," he said.
“I’m thrilled that we’re opening in Elstree, as I was born a stones-throw away in Hendon. It’s great to have a restaurant that’s so accessible to the residents of North London and surrounding areas.”
Gary Davis, chief executive of Village Hotels, said the first four Buca di Beppo restaurants had already proved a success within its other hotels.
"The British public have taken to the family dining Italian concept,” he said.
Buca di Beppo serves 'family-style' dishes with generous portions designed to be shared. Its menus include antipasti dishes ranging from £4.95 to £7.95, larger meat dishes from £10.95 and a variety of traditional Italian deserts starting at £4.45.